\nOamenii de \u015ftiin\u0163\u0103 care au realizat cercetarea au declarat c\u0103 testul ar putea \u201erevolu\u0163iona\u201d diagnosticarea precoce a bolii Parkinson, \u201edeschiz\u00e2nd calea pentru interven\u0163ii \u00een timp util \u015fi rezultate \u00eembun\u0103t\u0103\u0163ite pentru pacien\u0163i\u201d.<\/p>\n
\nBoala Parkinson este o afec\u0163iune neurologic\u0103 progresiv\u0103 \u00een care celulele nervoase din creier se pierd \u00een timp. Aceasta duce la o reducere a dopaminei chimice, care joac\u0103 un rol important \u00een controlul mi\u015fc\u0103rii.<\/p>\n
\nAcest nou test, care, potrivit Times, cost\u0103 80 de lire sterline, analizeaz\u0103 mici fragmente de material genetic cunoscute sub numele de fragmente de ARN de transfer (RFT) din s\u00e2nge, concentr\u00e2ndu-se pe o secven\u0163\u0103 repetitiv\u0103 de ARN care se acumuleaz\u0103 la pacien\u0163ii cu Parkinson.<\/p>\n
\nAcesta analizeaz\u0103, de asemenea, o sc\u0103dere paralel\u0103 \u00een ARN-ul mitocondrial, care se deterioreaz\u0103 pe m\u0103sur\u0103 ce boala progreseaz\u0103. Mitocondriile exist\u0103 \u00een interiorul celulelor \u015fi genereaz\u0103 energie.<\/p>\n
\nPrin m\u0103surarea raportului dintre ace\u015fti biomarkeri, cercet\u0103torii au declarat c\u0103 testul \u201eofer\u0103 un instrument de diagnostic extrem de precis, neinvaziv, rapid \u015fi accesibil, oferind speran\u0163e pentru interven\u0163ii \u015fi tratamente timpurii care ar putea schimba cursul bolii\u201d.<\/p>\n
\nPe o scar\u0103 \u00een care un scor de 1 indic\u0103 un test perfect, \u00een timp ce 0,5 arat\u0103 c\u0103 testul nu este bun, testul a ob\u0163inut un scor de 0,86. Cele mai bune teste clinice folosite \u00een prezent pe pacien\u0163ii care prezint\u0103 semne timpurii ale bolii au ob\u0163inut un scor de 0,73, potrivit studiului publicat \u00een revista Nature Aging, citat de The Guardian.<\/p>\n
\nTestul utilizeaz\u0103 aceea\u015fi tehnologie PCR folosit\u0103 \u00een timpul pandemiei pentru a confirma cazurile de Covid. Aceasta func\u0163ioneaz\u0103 prin amplificarea materialului genetic vizat, ceea ce permite detectarea acestuia.<\/p>\n","protected":false},"excerpt":{"rendered":"
Cercet\u0103torii au dezvoltat un test de s\u00e2nge simplu \u015fi \u201erentabil\u201d, capabil s\u0103 detecteze boala Parkinson cu mult \u00eenainte de apari\u0163ia simptomelor, conform unui studiu.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[37640,6],"class_list":["post-235683","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-parkinson","tag-test"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/235683","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=235683"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/235683\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=235683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=235683"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=235683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}