\nEchipa de la Centrul de medicin\u0103 regenerativ\u0103 UCLA a creat un medicament care poate \u00eempiedica formarea \u0163esutului cicatricial \u00een inim\u0103, principala cauz\u0103 a insuficien\u0163ei cardiace post-infarct.<\/p>\n
\n\u00cen prezent, jum\u0103tate dintre pacien\u0163ii care dezvolt\u0103 insuficien\u0163\u0103 cardiac\u0103 dup\u0103 infarct nu supravie\u0163uiesc mai mult de cinci ani, scrie shiawaves.com.<\/p>\n
\n\u201e\u00cen ciuda frecven\u0163ei atacurilor de cord, op\u0163iunile de tratament au r\u0103mas neschimbate \u00een ultimele decenii”, explic\u0103 dr. Arjun Deb, coordonatorul studiului.<\/p>\n
\nNoua terapie folose\u015fte un anticorp special conceput pentru a bloca proteina ENPP1, care provoac\u0103 inflama\u0163ie \u015fi cicatrici \u00een inim\u0103 dup\u0103 infarct.<\/p>\n
\nTestele pe \u015foareci au dat rezultate spectaculoase: doar 5% dintre animalele tratate au dezvoltat insuficien\u0163\u0103 cardiac\u0103 sever\u0103, \u00een grupul netratat, 52% au avut probleme grave. De asemenea, o singur\u0103 doz\u0103 de medicament a fost suficient\u0103 pentru a \u00eembun\u0103t\u0103\u0163i semnificativ vindecarea inimii.<\/p>\n
\nCercet\u0103torii pl\u0103nuiesc s\u0103 \u00eenceap\u0103 testele pe oameni la \u00eenceputul anului 2025. Pacien\u0163ii ar urma s\u0103 primeasc\u0103 o singur\u0103 doz\u0103 de medicament imediat dup\u0103 infarct, \u00een perioada critic\u0103 pentru vindecare.<\/p>\n
\n\u201eEste posibil s\u0103 descoperim o nou\u0103 clas\u0103 de medicamente care \u00eembun\u0103t\u0103\u0163esc repararea \u0163esuturilor”, spune dr. Deb, suger\u00e2nd c\u0103 tratamentul ar putea fi folosit \u00een viitor \u015fi pentru alte organe.<\/p>\n","protected":false},"excerpt":{"rendered":"
Dup\u0103 un infarct, inima are o capacitate foarte limitat\u0103 de a se regenera \u015fi dezvolt\u0103 cicatrici pentru a-\u015fi men\u0163ine structura. Cicatricile \u00eempiedic\u0103 inima s\u0103 pompeze s\u00e2ngele eficient, duc\u00e2nd adesea la insuficien\u0163\u0103 cardiac\u0103. Acum, cercet\u0103torii au dezvoltat o terapie care ar putea schimba situa\u0163ia.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[25380,12923],"class_list":["post-231266","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-infarct","tag-tratament"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/231266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=231266"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/231266\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=231266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=231266"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=231266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}