\nPersoanele care sufer\u0103 de steatohepatit\u0103 nealcoolic\u0103, adic\u0103 ficat gras non-alcoolic, dezvolt\u0103 forme grave de COVID-19. Un studiu realizat \u00een Spania spune c\u0103 afec\u0163iunea este o adev\u0103rat\u0103 poart\u0103 de intrare pentru coronavirus, mai ales dac\u0103 pacientul sufer\u0103 de obezitate. <\/p>\n
\nAnalizele realizate de mai mul\u0163i cercet\u0103tori intena\u0163ionali au fost coordonate de Laboratorul de Medicin\u0103 Molecular\u0103 de la Universitatea din Santiago de Compostela.<\/p>\n
S-a descoperit c\u0103 acolo unde steatohepatita nealcoolic\u0103, adic\u0103 ficatul gras non-alcoolic, este asociat\u0103 de obezitate se vede o reac\u0163ie mai mare \u00eentre enzima ACE2 \u015fi Tmprss2, o molecul\u0103 care permite uniunea dintre membrana virusului \u015fi celul\u0103.<\/p>\n
Cel pu\u0163in 80% din pacien\u0163ii cu forme grave de COVID-19 din Spania sufer\u0103 de obezitate \u015fi printre simptomele cele mai \u00eent\u00e2lnite se num\u0103r\u0103 \u015fi insuficien\u0163a hepatic\u0103.<\/p>\n
Studiile medicilor spanioli arat\u0103 \u00een acela\u015fi timp c\u0103 virusul nu are aceea\u015fi posibilitate de a \u00eemboln\u0103vi persoanele care sufer\u0103 de steatoz\u0103, chiar dac\u0103 prezint\u0103 \u015fi obezitate sau diabet de tip 2.<\/p>\n
\n\u201eDescoperirile noastre sugereaz\u0103 c\u0103 b\u0103rba\u0163ii obezi, afecta\u0163i de o boal\u0103 hepatic\u0103 prin acumulare de gr\u0103sime \u015fi dac\u0103 aceasta este avansat\u0103 prezint\u0103 simptomer grave de COVID, pentru c\u0103 au o activitate crescut\u0103 a uneia dintre moleculele absolut indispensabile pentru ca virusul s\u0103 intre. Se explic\u0103 astfel de ce b\u0103rba\u0163ii obezi cu acumulare de gr\u0103sime la ficat au simptome mai grave de COVID-19, \u00een compara\u0163ie cu femeile care au o stimulare mai mic\u0103 a acestui receptor numit ACE2 \u015fi cu cei care nu au aceast\u0103 afec\u0163iune hepatic\u0103. Este adev\u0103rat c\u0103 acum este doar o posibilitate, dar putem s\u0103 ne g\u00e2ndim c\u0103 acest grup de pacien\u0163i cu boli prin acumulare de gr\u0103sime, \u00een form\u0103 avansat\u0103… Este important de spus asta. Deci nu to\u0163i. De ce s\u0103 nu fie acest grup prioritar pentru vaccinuri atunci c\u00e2nd vor fi gata?\u201d, spune dr. Javier Crespo, pre\u015fedintele Societ\u0103\u0163ii Spaniole de Patologie Digestiv\u0103.<\/p>\n
\nRezultatele cercet\u0103rilor au fost publicate \u00een Journal of Hepatology \u015fi vizeaz\u0103 aproape 2 miliarde de oameni din lume.<\/p>\n","protected":false},"excerpt":{"rendered":"
Persoanele care sufer\u0103 de steatohepatit\u0103 nealcoolic\u0103, adic\u0103 ficat gras non-alcoolic, dezvolt\u0103 forme grave de COVID-19. Un studiu realizat \u00een Spania spune c\u0103 afec\u0163iunea este o adev\u0103rat\u0103 poart\u0103 de intrare pentru coronavirus, mai ales dac\u0103 pacientul sufer\u0103 de obezitate. Analizele realizate de mai mul\u0163i cercet\u0103tori intena\u0163ionali au fost coordonate de Laboratorul de Medicin\u0103 Molecular\u0103 de la […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[14023,46034,7853],"class_list":["post-187467","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-boala","tag-coronavirus","tag-studiu"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/187467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=187467"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/187467\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=187467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=187467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=187467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}