\nAceast\u0103 reu\u015fit\u0103 medical\u0103 a fost anun\u0163at\u0103 de o echip\u0103 de cercet\u0103tori din New York, al c\u0103rei studiu a fost prezentat \u00eentr-un articol ap\u0103rut \u00een urm\u0103 cu c\u00e2teva zile \u00een publica\u0163ia The New England Journal of Medicine.<\/p>\n
\nPentru tratarea acelei paciente, medicii au combinat doi anticorpi: ipilimumab (principiul activ din medicamentul Yervoy, utilizat pentru tratarea melanomului avansat la adul\u0163i) \u015fi nivolumab (autorizat \u00een Statele Unite sub numele Opdivo).<\/p>\n
\n“Atunci c\u00e2nd a revenit la control, dup\u0103 trei s\u0103pt\u0103m\u00e2ni, pentru o nou\u0103 doz\u0103 de tratament, am putut s\u0103 constat\u0103m c\u0103 tumoarea disp\u0103ruse. \u00cen locul ei r\u0103m\u0103sese doar o cavitate”<\/strong>, afirm\u0103 autorii studiului.<\/p>\n \nFemeia respectiv\u0103 a fost primul pacient care a reac\u0163ionat at\u00e2t de rapid la acel cocktail de medicamente. \u00centr-un articol publicat tot \u00een The New England Journal of Medicine, oamenii de \u015ftiin\u0163\u0103 newyorkezi au precizat faptul c\u0103 au comparat analizele pacien\u0163ilor trata\u0163i cu acea combina\u0163ie (ipilimumab \u015fi nivolumab) cu datele provenind de la pacien\u0163i trata\u0163i cu ipilimumab \u015fi un placebo.<\/p>\n \nPotrivit acestui studiu, 61% dintre pacien\u0163ii din primul grup au beneficiat de o reducere a tumorilor canceroase. \u00cen cel de-al doilea grup, acest procent a fost de 11%. De asemenea, doar pacien\u0163ii care au primit acel cocktail de medicamente au beneficiat de o dispari\u0163ie complet\u0103 a melanomului (22% din totalul cazurilor).<\/p>\n \nTotu\u015fi, aceast\u0103 combina\u0163ie de medicamente, ale c\u0103ror efecte prezint\u0103 diferen\u0163e mari de la un pacient la altul, provoac\u0103 efecte secundare importante, precum inflama\u0163ii ale colonului, func\u0163ionarea anormal\u0103 a glandelor endocrine \u015fi diaree.<\/strong><\/p>\n \nPotrivit studiului newyorkez, 54% dintre pacien\u0163ii trata\u0163i cu cele dou\u0103 medicamente au suferit efecte secundare indezirabile. Prin compara\u0163ie, 24% dintre pacien\u0163ii trata\u0163i doar cu ipilimumab au prezentat astfel de efecte.<\/p>\n \nDe asemenea, pre\u0163urile acestor medicamente r\u0103m\u00e2n ridicate. Pentru patru \u015fedin\u0163e, ipilimumabul cost\u0103 120.000 de dolari, iar pacien\u0163ii c\u0103rora le este administrat nivolumab vreme de un an trebuie s\u0103 pl\u0103teasc\u0103 150.000 de dolari, precizeaz\u0103 Wall Street Journal.<\/p>\n","protected":false},"excerpt":{"rendered":" Un nou cocktail de medicamente a permis dispari\u0163ia, \u00een doar trei s\u0103pt\u0103m\u00e2ni, a unui melanom metastazat cu care fusese diagnosticat\u0103 o pacient\u0103 \u00een v\u00e2rst\u0103 de 49 de ani, informeaz\u0103 site-ul slate.fr.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[14610,323,23055],"class_list":["post-121255","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-cancer","tag-medicamente","tag-melanom"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/121255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=121255"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/121255\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=121255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=121255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=121255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}