\n\u00cen noul s\u0103u raport, dat publicit\u0103\u0163ii luni, Comitetul de evaluare a riscurilor \u00een materie de farmaco-vigilen\u0163\u0103 (PRAC) din cadrul EMA a subliniat faptul c\u0103 aceast\u0103 cre\u015ftere a riscului cardiovascular \u00eei vizeaz\u0103 doar pe acei pacien\u0163i care iau doze de ibuprofen mai mari de 2.400 de miligrame pe zi.<\/p>\n
\n\u00cen schimb, cercet\u0103torii nu au observat niciun risc la pacien\u0163ii care iau acest medicament \u00een doze mai mici de 1.200 de miligrame pe zi – a\u015fa cum procedeaz\u0103 cei mai mul\u0163i dintre bolnavi. Dozele obi\u015fnuite la adul\u0163i variaz\u0103 \u00eentre 200 \u015fi 400 de miligrame de trei ori pe zi.<\/p>\n
\nIbuprofenul este un medicament comercializat \u00eencep\u00e2nd din anii 1960 sub diverse nume. Anumite formule ale sale (\u00een special cele de 200 miligrame) se v\u00e2nd la liber, f\u0103r\u0103 re\u0163et\u0103, \u00een mai multe \u0163\u0103ri europene, inclusiv \u00een Rom\u00e2nia.<\/p>\n
\nPotrivit PRAC, riscul cardiovascular generat de ibuprofen \u00een doze mari este similar cu cel generat de analgezicul diclofenac (voltaren \u015fi alte denumiri), a c\u0103rui utilizare a fost deja restr\u00e2ns\u0103 din 2013 pentru pacien\u0163ii care au anumite probleme cardiovasculare.<\/p>\n
\n\u00cen consecin\u0163\u0103, PRAC preconizeaz\u0103 modificarea prescrip\u0163iilor medicale \u015fi \u00eei \u00eendeamn\u0103 pe medici s\u0103 evalueze “cu aten\u0163ie” riscurile cardiovasculare ale pacien\u0163ilor \u00eenainte de a prescrie ibuprofen pe durat\u0103 mare \u015fi \u00een doze importante.<\/p>\n
\nAvizul PRAC vizeaz\u0103 doar tratamentele administrate pe cale oral\u0103, nu gelurile \u015fi cremele pe baz\u0103 de ibuprofen.<\/p>\n
\n\u00centruc\u00e2t medicamentele pe baz\u0103 de ibuprofen sunt deja aprobate la nivel na\u0163ional, recomand\u0103rile formulate de PRAC vor trebui s\u0103 fie mai \u00eent\u00e2i aprobate de Comitetul european de coordonare (CMDh), entitatea european\u0103 care reprezint\u0103 diversele agen\u0163ii na\u0163ionale ale medicamentului.<\/p>\n","protected":false},"excerpt":{"rendered":"
Ibuprofenul, unul dintre medicamentele cele mai utilizate \u00eempotriva durerilor \u015fi a inflama\u0163iilor, cre\u015fte riscul de infarct \u015fi de accident vascular cerebral (AVC), \u00eens\u0103 doar atunci c\u00e2nd este administrat \u00een doze foarte puternice, afirm\u0103 Agen\u0163ia European\u0103 a Medicamentului (EMA), potrivit lesechos.fr.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[40199,37520,9184],"class_list":["post-120590","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-avc","tag-ibuprofen","tag-risc"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/120590","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=120590"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/120590\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=120590"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=120590"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=120590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}