\nBifosfona\u0163ii blocheaz\u0103 \u00een aceste cancere ac\u0163iunea proteinelor – denumite receptori ai factorului de cre\u015ftere epidermic\u0103 (HER) – care, de obicei, accelereaz\u0103 proliferarea celulelor canceroase.<\/p>\n
\nAceste caracteristici anticancer ale bifosfona\u0163ilor, comercializa\u0163i \u015fi sub denumirile Fosamax \u015fi Zometa, au fost deja observate la femeile diagnosticate cu cancer mamar.<\/strong><\/p>\n \nMedicii au observat, de asemenea, c\u0103 pacien\u0163ii care luau bifosfona\u0163i pe cale oral\u0103 pentru tratarea osteoporozei prezentau o inciden\u0163\u0103 mai sc\u0103zut\u0103 de cancer la colon \u015fi mamar, demonstr\u00e2nd virtu\u0163ile preventive ale acestui tratament.<\/p>\n \n“Studiul nostru a eviden\u0163iat un mecanism care ar putea s\u0103 permit\u0103 folosirea bifosfona\u0163ilor \u00een tratarea \u015fi prevenirea unui num\u0103r mare de cancere pulmonare, mamare \u015fi de colon, a c\u0103ror agresivitate este alimentat\u0103 de receptorii HER”<\/strong>, explic\u0103 profesorul Mone Zaidi, profesor la Facultatea de medicin\u0103 Mount Sinai din New York, membr\u0103 a echipei interna\u0163ionale care a realizat acest studiu, ap\u0103rut \u00een Proceedings of the National Academy of Sciences (PNAS).<\/p>\n \nDac\u0103 testele clinice confirm\u0103 efectele anticancer ale bifosfona\u0163ilor, aceste medicamente ar putea fi utilizate foarte repede \u00een spitale, \u00eentruc\u00e2t sunt deja aprobate de Agen\u0163ia american\u0103 pentru medicamente (FDA).<\/p>\n \nBifosfona\u0163ii ar putea reprezenta un aport consistent \u00een arsenalul terapeutic \u00eempotriva cancerelor de pl\u0103m\u00e2n, de colon \u015fi de s\u00e2n. Pacien\u0163ii diagnostica\u0163i cu aceste trei tipuri de cancer sunt purt\u0103tori ai acestei gene \u00een 30%, 90% respectiv 20% din cazuri.<\/p>\n","protected":false},"excerpt":{"rendered":" Bifosfona\u0163ii, administra\u0163i ca tratament de baz\u0103 pentru prevenirea \u015fi tratarea osteoporozei, sunt eficien\u0163i \u015fi \u00eempotriva anumitor tipuri agresive de cancer pulmonar, mamar \u015fi de colon, potrivit unor experimente efectuate pe \u015foareci \u015fi pe celule umane, ale c\u0103ror rezultate au fost prezentate luni.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[510],"tags":[38881,14610,10857],"class_list":["post-114936","post","type-post","status-publish","format-standard","hentry","category-actualitate","tag-bifosfonati","tag-cancer","tag-osteoporoza"],"_links":{"self":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/114936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=114936"}],"version-history":[{"count":0,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=\/wp\/v2\/posts\/114936\/revisions"}],"wp:attachment":[{"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=114936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=114936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bm.dev.synology.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=114936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}